Center for Translational Cancer Research
In a powerful model of public-private partnership, IISER Pune and Prashanti Cancer Care Mission will bring together clinicians and researchers to integrate cancer research, training, and education. This Centre will be a first-of-its-kind initiative in India with world-class infrastructure and facilities for multidisciplinary training in translational cancer research. We anticipate that the activities of the Centre will have a direct positive impact on the national capacity for translational cancer research and, most importantly, on effective management of cancer in India.
CTCR is initiated with a seed grant from Bajaj Auto.
Ongoing Research Projects at Centre for Translational Research
Clinical Research
Breast Oncoplastic Surgery
(Role as Principal Investigator)
- Breast-Q based evaluation of patient-reported outcomes (PROMs) after breast oncoplastic surgery
- Extreme oncoplastic surgery for multicentric/multifocal and locally advanced breast cancers
- Immediate breast reconstruction surgery using implants and autologous lower dermal sling (ALDS) procedure
- Immediate breast reconstruction surgery in small and non-ptotic breasts with advanced autologous lower dermal sling technique procedure
- Breast reconstruction audit
- Therapeutic mammoplasty audit
- Radiology
(Role as Co-Principal Investigator)
- Breast angiosarcoma: A Case Study
- Clip insertion technique for tumor localization – A Case Series
- Development of a machine learning algorithm for ultrasound based differential evaluation of breast cancer clinical subtypes
- Evaluation of Breast Elastography for differential diagnosis of TNBCs.
- Radio-genomic evaluation of BRCA-mutated Breast Cancers
- Chemotherapy
(Role as Co-Principal Investigator)
- Evaluating role of neo-adjuvant chemotherapy (NACT) in breast surgery outcomes
- Radiation Oncolog
(Role as Co-Principal Investigator; Collaboration with Inlaks and Budhrani Hospital)
- Breast Oncoplasty and radiation therapy outcomes
- Accelerated partial breast irradiation (APBI) audit
- Simultaneous-integrated boost (SIB) intensity modulated radiation therapy for Breast Oncoplasty applications
- Translational Research
Molecular Oncology
(Role as Co-Principal Investigator; Collaboration with Indian Institute of Science Education and Research (IISER), Pune)
- Establishment of breast cancer biobank
- Investigating germ line and somatic mutation profiles in Indian triple negative breast cancer (TNBC) patients
- Characterizing TNBC heterogeneity and subtypes in Indian breast cancer patients
- Genetics of male breast cancer
- Molecular profiling of recurrent breast cancer with rectal metastasis.
- Investigating the role of HIPPO signaling in breast cancer carcinogenesis
- Characterizing novel signaling pathways in breast cancer progression
- Development of novel polymer-coated breast implants.
- Public Health Research
(Role as Principal Investigator)
- Evaluation on community based screening strategies for early detection of breast cancers